教师信息

宋蔚

作者:生命科学学院发布时间:2016年09月27日 00:00

姓  名: 宋蔚
办公电话: 027-88661237
电子邮件: belinde_83@163.com
通讯地址: 湖北省武汉市武昌区友谊大道368号湖北大学生命科学学院
任职情况:博士,现任湖北大学讲师
研究领域:药物分析、药物代谢动力学,新药临床前研究
 
一、学习和工作简历:
2001年9月-2005年7月,湖北大学生命科学学院,生物科学专业,获理学学士学位
2005年9月-2008年7月,湖北大学生命科学学院,微生物与生化药学专业,获医学硕士学位
2009年9月-2015年5月,华中科技大学生命科学学院,生物制药工程专业,获药学博士学位
2011年12月-2012年11月,美国圣母大学,访问学者
2016年1月-今,湖北大学生命科学学院讲师
 
 
二、代表性论文(*通讯作者):
1. Wei Song, Zhihong Peng, Major Gooyit, Mark A. Suckow, Valerie A. Schroeder, William R. Wolter, Mijoon Lee, Masahiro Ikejiri, Jiankun Cui, Zezong Gu, and Mayland Chang. Water-soluble MMP-9 inhibitor prodrug generates active metabolites that cross the blood-brain barrier. ACS Chem. Neurosci., 2013, 4 (8), 1168–1173.   
2. Wei Song, Longjiang Yu, Zhihong Peng. Targeted label-free approach for quantification of epoxide hydrolase and glutathione transferases in microsomes. Analytical Biochemistry. 2015, 478 (2015) 8–13 .
3. Wei Song, Mingzhang Ao,Yue Shi, Lingfang Yuan, Xinxia Yuan, Longjiang Yu. Interaction between Phillygenin and Human Serum Albumin based on Spectroscopic and Molecular docking. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy.  2012 Jan;85(1):120-6.
4. Wei Song, Zhihong Peng, Baoying Ge, Fengmei Han, Yong Chen. Identification of metabolites of lobeline in the rat urine by liquid chromatographytandem mass spectrometry. International Journal of Mass Spectrometry. 2008, 269(1-2):131-137. 
5.  Major Gooyit, Wei Song, Kiran V. Mahasenan, Katerina Lichtenwalter, Mark A. Suckow, Valerie A. Schroeder, William R. Wolter, Shahriar Mobashery, and Mayland ChangO-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood-Brain Barrier. Journal of Medicinal Chemistry, DOI: 10.1021/jm401217d. 
6. O’Daniel, P.I.; Peng, Z.; Pi, H.; Testero, S. A.; Ding, D.; Spink, E.; Leemans, E.; Boudreau, M. A.; Yamaguchi, T.; Schroeder, V. A.; Wolter, W. R.; Llarrull, L. I.; Song, W.; Lastochkin, E.; Kumarasiri, M.; Antunes, N. T.; Espahbodi, M.; Lichtenwalter, K.; Suckow, M. A.; Vakulenko, S.; Mobashery, S.; Chang, M. Discovery of a New Class of Non-β-Lactam Inhibitors of Penicillin-binding Proteins with Gram-positive Antibacterial Activity. J. Am. Chem. Soc. 2014, DOI: 10.1021/ja5000053x. In press. 
7. Yong Chen, Wei Song, Zhi H. Peng, Bao Y. Ge, Feng M. Han. Identification of metabolites of tectoridin in vivo and in vitro by liquid chromatography - tandem mass spectrometry. Journal of Pharmacy and Pharmacology. 2008, 60 (6): 709-716. 
8. Zhihong Peng, Wei Song, Fengmei Han, Huaixia Chen, Mingming Zhu, Yong Chen. Chromatographic Tandam Mass Spectrometric Detection of Papaverine and Its Major Metabolites in Rat Urine. International Journal of Mass Spectrometry. 2007, 266 (1-3): 114-121.  
9. Peng Zhihong, Song Wei, Han Fengmei, Chen Yong. In vivo and in vitro study of papaverine and its major metabolites. Acta Pharmaceutica Sinica. 2009, 44(1):95-100.
10. F.M. Han, Z.H. Peng, W. Song, H.M. Zhang, M.M. Zhu, Y. Chen. Identification of Dauricine and Its Metabolites in Rat Urine by Liquid Chromatography-Tandem Mass Spectrometry. Journal of Chromatogr B.  2007, 854 (1-2): 1-7. 
11. Y. Chen, Z. H. Peng, W. Song, M. M. Zhu, and F. M. Han. Chromatographic Tandem Mass Spectrometric Detection of Physostigmine and its Major Metabolites in Rat Urine. Analytical letters. 2007, 40(16-18): 3256-3266.