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  • 彭文舫
  • 作者:    发布日期:2017-11-20    点击率:
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    : 彭文舫

    : 13886111073(手机)

    电子邮件: wenfang@hubu.edu.cn

    通讯地址: 湖北省武汉市武昌区友谊大道368号,湖北大学生命科学学院,430062

    基本情况简介:博士,副教授,硕士研究生导师,2016年“楚天学子”

    主要研究领域:微生物学、微生物遗传学、CRISPR-Cas病毒免疫机制、分子酶工程

    ² 学习和工作简历

    · 2001/9-2005/7,长江大学,获农学学士学位

    · 2005/9-2008/7,中国农业科学院,获农学硕士学位

    · 2008/8-2010/8,中国农业科学院油料作物研究所,研究助理

    · 2010/9-2005/6,华中农业大学,获理学博士学位

    · 2012/7-2015/3University of Copenhagen, PhD in Biology

    · 2016/2-2016/12,国家自然科学基金委员会生命学部,借调

    · 2015/11-2017/6,湖北大学生命科学学院,讲师

    · 2017/7-今,湖北大学生命科学学院,副教授

    ² 主持/参与科研项目情况

    1. 湖北省自然科学基金面上项目-“基于嗜热古菌冰岛硫化叶菌CRISPR-Cas系统的DNA/RNA编辑平台的搭建和优化,在研,主持人

    2. 湖北省教育厅青年人才项目160801301002-“利用酵母内质网滞留系统促进人凝血因子IXFIX)高活性表达的研究,在研,主持人

    3. 湖北大学青年科学基金,冰岛硫化叶菌多个CRISPR-Cas系统病毒免疫协作机制,在研,主持人

    4. 丹麦独立研究(自然科学类)基金项目(DFF–1323-00330-“Functional analyses of archaeal Cas/Cmr modules and their integration and cooperation in antiviral defense”,结题,参与人

    5. 国家自然科学基金海外及港澳学者合作研究基金(31128011-“极端嗜热古菌CRISPR/Cas 系统的功能研究,结题,参与人

    6. 国家自然科学基金面上项目(30571132-“中国花生核心种质的构建及重要新基因源发掘,结题,参与人

    7. 国家自然科学基金面上项目(30471062-“花生种子贮藏蛋白在抗黄曲霉产毒中的作用于遗传分析,结题,参与人

    8. 楚天学专项经费,负责

     

    ² 代表性研究论文

    1. Wenfang Peng#, Mingxia Feng, Xu Feng, Yun Xiang Liang & Qunxin She* (2015). "An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference." Nucleic Acids Research 43(1): 406-417. IF=9.202

    2. Wenfang Peng#, Huan Li, Søren Hallstrøm, Nan Peng, Yun Xiang Liang & Qunxin She* (2013). "Genetic determinants of PAM-dependent DNA targeting and pre-crRNA processing in Sulfolobus islandicus." RNA Biology 10(5): 738-748. IF=5.377

    3. Wenyuan Han#, Yingjun Li#, Ling Deng, Mingxia Feng, Wenfang Peng, Søren Hallstrøm, Jing Zhang, Nan Peng, Yun Xiang Liang, Malcolm F. White & Qunxin She* (2017). "A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction." Nucleic Acids Research 45(4): 1983-1993. IF=10.162

    4. Fei He#, Gisle Vestergaard, Wenfang Peng, Qunxin She & Xu Peng* (2017). "CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b." Nucleic Acids Research 45(4): 1902-1913. IF=10.162

    5. Roger A. Garrett*, Shiraz A. Shah, Susanne Erdmann, Guannan Liu, Marzieh Mousaei, Carlos Leon-Sobrino, Wenfang Peng, Soley Gudbergsdottir, Ling Deng, Gisle Vestergaard, Xu Peng & Q. She (2015). "CRISPR-Cas adaptive immune systems of the Sulfolobales: Unravelling their complexity and diversity." Life (Basel) 5(1): 783-817.

    6. Meng Mei#, Yu Zhou, Wenfang Peng, Chan Yu, Lixin Ma, Guimin Zhang* & Li Yi* (2017). "Application of modified yeast surface display technologies for non-antibody protein engineering." Microbiological Research 196: 118-128. IF=3.037

    7. Tao Liu#, Zhenzhen Liu, Qing Ye, Saifu Pan, Xiaodi Wang, Wenfang Peng, Yingjun Li, Yun Xiang Liang, Qunxin She & Nan Peng* (2017). “Coupling transcriptional activation of CRISPR-Cas system and DNA repair genes by Csa3a in Sulfolobus islandicus.” Ncleic Acids Research DOI: 10.1093/nar/gkx612. IF=10.162

    8. Meng Mei#, Chao Zhai, Xinzhi Li, Yu Zhou, Wenfang Peng, Lixin Ma, Qinhong Wang, Brent L. Iverson, Guimin Zhang* & Li Yi*. (2017) Journal of Bioligical Chemistry DOI: 10.1047/jbc.M117.812107

    9. Wenfang Peng#, Jianwei Lv, Xiping Ren, Li Huang, Xinyan Zhao, Qigen Wen & Huifang Jiang* (2011) Differential expression of genes related to bacterial wilt resistance in peanut (Arachis hypogaea L.). Yichuan 33(4), 389-396. (in Chinese)

    10. Wenfang Peng#, Xiaoping Ren, Jianwei Lv, Xinyan Zhao, Li Huang & Huifang Jiang (2010) Construction of AFLP genetic linkage map and detection of QTLs for bacterial wilt resistance in peanut (Arachis hypogaea L.). Acta Agriculturae Boreali-Sinica 25(6), 81-86. (in Chinese)

    11. Jianwei Lv#, Jiaquan Huang, Wenfang Peng, Yuning Chen, Zhengqiang Li & Huifang Jiang* (2011) Analysis of gene expression profiles in response to Ralstonia solanacearum using SSH in peanut. Acta Botanica Boreali-Occidentalia Sinica 31(8), 1517-1523. (in Chinese)

    ² 专利申请/授权情况

    1. 易犁,周瑜,张桂敏,彭文舫,马立新,马延和 (2016) 一组不同启动子介导的蛋白酶高通量筛选载体及筛选方法 (CN201510802312.9).

    2. 易犁,范贤,彭文舫,周瑜,喻婵,张桂敏(2017)一种切割效率增强的HRV3C蛋白酶底物突变体及其应用 (CN201710956966.6).

    ² 参加学术会议情况

    1. Wenfang Peng & Qunxin She. Revealing in vivo RNA interference activity of type III CRISPR systems in Sulfolobus islandicus. Functional Genomics Summer Symposium 2014 in Copenhagen, Denmark . Speaker.

    2. Wenfang Peng & Qunxin She. Genetic analysis of CRISPR-Cas systems in Sulfolobus islandicus. Functional Genomics Summer Symposium 2013 in Copenhagen, Denmark . Speaker.

    3. Wenfang Peng & Qunxin She. Characterizing the CRISPR-mediated RNA targeting activity in Sulfolobus in vivo, FOR1680 Meeting in Copenhagen, Denmark . 2013. Speaker.

    4. 彭文舫,易犁,Qunxin She. 2017中国微生物学会学术年会. 郑州,口头报告

    5. Wenfang Peng & Qunxin She. In vivo RNA interference directed by CRISPR-Cmr systems in Sulfolobus islandicus. FOR1680 Meeting in Marburg, Germany . 2012. Poster.

    6. Wenfang Peng, Søren Hallstrøm & Qunxin She. Multiple CRISPR-Cas modules in Sulfolobus islandicus: Independent or integrated mode of action in viral silencing. FOR1680 Meeting in Kiel, Germany . 2011. Poster.

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