一、基本信息
王勤,博士,副教授,硕士生导师
办公电话:027-88668081
电子邮件:qin.wang(AT)hubu.edu.cn
研究领域:微生物代谢工程, 生物材料学
二、教育背景
2006.08–2012.05 美国纽约州立大学环境科学与森林学学院化学系,博士
2003.09–2006.06 南京大学环境学院,硕士
1999.09–2003.06 南京大学环境学院,学士
三、工作经历
1. 副教授–湖北大学生命科学学院 陈守文教授研究团队
Ÿ 构建胞外生产弹性丝蛋白的重组地衣芽孢杆菌
Ÿ 构建高产杆菌肽地衣芽孢杆菌菌株
Ÿ 地衣芽孢杆菌中氨基酸代谢调控机理研
2. 博士后研究员—塔夫斯大学(Tufts University)生物医学工程系,David L. Kaplan 教授实验室
Ÿ 构建转基因大肠杆菌生产重组蜘蛛丝蛋白
Ÿ 文库构建和高通量筛选重组弹性丝蛋白(silk elastin like proteins)
Ÿ 生物发酵工程优化生产重组弹性丝蛋白
3. 讲师—塔夫斯大学 (Tufts University)生物医学工程专业,重组DNA技术课程
4. 研究助理-纽约州立大学环境科学与森林学学院化学专业,Christopher T. Nomura教授实验室
Ÿ 基因表达水平监测和代谢途径鉴定可降解塑料聚羟基脂肪酸酯 (PHA)生产细菌, Pseudomonas putida.
Ÿ 构建转基因大肠杆菌从廉价碳源中生产中链聚羟基脂肪酸酯 (medium-chain-length PHA)
Ÿ 中短链聚羟基脂肪酸酯共聚物 (medium-chain-length-short-chain-length PHA)物理和机械性质测试
四、科研项目
1. 湖北省自然科学基金(2015CFB214):动态生物材料弹性丝蛋白(Silk-Elastin-Like Proteins)在地衣芽胞杆菌中的生产及优化,2015/01–2016/12, 主持人
五、代表著作(#共同第一作者,*通讯作者)
1. Liang C, Huo Y, Qi G, Wei X, Wang Q, Chen S. (2015) Enhancement of L–valine production in Bacillus licheniformis by blocking three branched pathways, Biotechnology Letters 37, 1243−1248.
2. Wang Q, Xia X, Huang W, Lin Y, Xu Q, Kaplan DL. (2014) High throughput screening of dynamic silk-elastin-like protein biomaterials. Advanced Functional Materials 24, 4303−4310.
3. Wang Q, Zhu C, Yancone T, Nomura CT. (2012) The effect of co-substrate feeding on polyhydroxyalkanoate (PHA) homopolymer and copolymer production in recombinant Escherichia coli LS5218. Journal of Bioprocess Engineering and Biorefinery 1, 86−92.
4. Wang Q, Tappel RC, Zhu C., Nomura CT. (2012) Development of a new strategy for production of medium-chain-length polyhydroxyalkanoates (MCL-PHAs) by recombinant Escherichia coli via inexpensive non-fatty acid feedstocks. Applied and Environmental Microbiology 78, 519−527.
5. Tappel RC, Wang Q, Nomura CT*. (2012) Precise control of repeating unit composition of poly(3-hydroxyalkanoates) synthesized by recombinant Escherichia coli. Journal of Bioscience and Bioengineering 113, 480−486.
6. Wang Q, Nomura CT. (2010) Monitoring differences in gene expression levels and polyhydroxyalkanoate (PHA) production in Pseudomonas putidaKT2440 grown on different carbon sources. Journal of Bioscience and Bioengineering 110, 653−659.
7. Wang Q, Mueller AP, Leong CR, Matsumoto K., Taguchi S, Nomura CT (2010) Quick and efficient method for genetic transformation of biopolymer-producing bacteria. Journal of Chemical Technology and Biotechnology 85, 775−778.
8. Wang Q, Nomura CT. (2010). A survey of biodegradable plastics in the U.S. BioPlastic Journal 36, 13−19.
9. Wang Q, Zhao Q, Xiao L, Yang L. (2006) Soluble phosphorus removed by the Escherichia coli transformed with polyphosphate kinase gene. China Environmental Science 6, 21−27.
六、专利 :
1. Nomura, CT, Tappel RC, Wang Q. (2012) Engineered strain for the production of specific R-3-hydroxyalkanoic acids and poly-R-3-hydroxyalkanoate polymers with defined monomer unit composition. Provisional Patent Application 1279_015PRO. Filed January 9, 2012.
七、获奖
1. Tore E. Timell 化学杰出贡献奖(2011)
2. Ernest Sondheimer 优秀化学研究奖(2010)
3. Michael Szwarc 优秀化学研究奖(2009)
4. Eastman 优秀研究生(2009)