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肖盼

作者:  发布时间:2023-09-15  阅读次数:

一、基本信息

肖盼,博士,讲师

电子邮件:xiaopan@hubu.edu.cn

研究方向:化学生物学,生物催化

二、教育背景

2017.10-2021.04  诺曼底大学-法国鲁昂国立应用科学学院,化学,理学博士

2014.09-2017.07  中国科学院上海有机化学研究所,有机氟化学重点实验室,有机化学,理学硕士

2010.09-2014.06  湖北大学化学化工学院,化学生物学,学士

三、工作经历

2023.08至今        湖北大学,省部共建生物催化与酶工程国家重点实验室,讲师

2021.06-2023.07  国科大杭州高等研究院/中国科学院上海药物研究所联合培养,药物科学与技术学院,博士后

四、代表性论文(#共同第一作者)

1. Xiao P#, Duan Z#, Liu Z#, Chen L, Zhang D, Liu L, Zhou C, Gan J, Dong Z, Yang C-G, Rational Design of RNA Demethylase FTO Inhibitors with Enhanced Antileukemia Drug-Like Properties. J Med Chem 2023, 66 (14), 9731-9752.

2. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Wonderful fusion of organofluorine chemistry and decarboxylation strategy. Chem Soc Rev 2021, 50 (10), 6094-6151.

3. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Palladium-Catalysed Oxidative Decarboxylative Cross-Coupling of Heteroarenes with CF3-Acrylic Acids. ChemistrySelect 2021, 6 (29), 7367-7371.

4. Xiao P, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Ligand Free Palladium-Catalyzed Synthesis of α-Trifluoromethylacrylic Acids and Related Acrylates by Three-Component Reaction. Adv Synth Catal 2020, 362 (4), 949-954.

5. Xiao P, Schlinquer C, Pannecoucke X, Couve-Bonnaire S, Bouillon J-P, Ligand-free palladium-catalyzed Mizoroki-Heck reaction to synthesize valuable α-trifluoromethylacrylates. J Fluorine Chem 2020, 233, 109483.

6. Xiao P, Schlinquer C, Pannecoucke X, Bouillon J-P, Couve-Bonnaire S, Synthesis of α-Trifluoromethylacrylates by Ligand-Free Palladium-Catalyzed Mizoroki-Heck Reaction. J Org Chem 2019, 84 (4), 2072-2082.

7. Xiao P, Ni C, Miao W, Zhou M, Hu J, Chen D, Hu J, Fluoroalkylation of Various Nucleophiles with Fluoroalkyl Sulfones through a Single Electron Transfer Process. J Org Chem 2019, 84 (13), 8345-8359.

8. Xiao P, Rong J, Ni C, Guo J, Li X, Chen D, Hu J, Radical (Phenylsulfonyl)difluoromethylation of Isocyanides with PhSO2CF2H under Transition-Metal-Free Conditions. Org Lett 2016, 18 (22), 5912-5915.

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