一、 基本信息
高卫杰,博士,讲师
电子邮箱:gaowj@hubu.edu.cn
研究领域:干细胞生物学,微器官构建,心脏疾病机理
二、 教育背景
2015.08–2018.10 香港中文大学,生物医学学院,生物医学博士
2010.09–2013.07 华南师范大学,生物光子学研究院,生物物理学硕士
2006.09–2010.07 河南师范大学,生命科学学院,理学学士
三、 工作经历
2023.08至今 湖北大学,生命科学学院,讲师
2020.07–2023.07 中山大学肿瘤防治中心,博士后,合作导师:康铁邦研究员
2018.11–2020.06 香港中文大学,Research Associate/博士后,合作导师:Franky Leung CHAN 教授
四、科研项目
1. 广东省海外博士后人才支持项目,2021-2023, 主持
2. 国家自然科学基金面上项目(32370819),MYBL2-RAN促进骨肉瘤干细胞生长的调控机制及临床意义,2024.01-2027.12,50万元,参与
3. 香港研究资助局General Research Fund(14107617),Elucidating the role of endothelial nitric oxide synthase (eNOS) in prostate cancer,2018.07-2021.06,101.8万港元,参与
五、代表性论文(#共同一作)
1. Gao W, Wang Y, Yu S, Wang Z, Ma T, Chan A, Chiu P, Ng C, Wu D, Chan F. Endothelial nitric oxide synthase (eNOS)-NO signaling axis functions to promote the growth of prostate cancer stem-like cells. Stem Cell Res Ther. 2022; 13(1):188.
2. Gao W, Wu D, Wang Y, Wang Z, Zou C, Dai Y, Ng C, Teoh J, Chan F. Development of a novel and economical agar-based non-adherent three-dimensional culture method for enrichment of cancer stem-like cells. Stem Cell Res Ther. 2018; 9(1):243.
3. Wang Y, Gao W, Li Y, Chow S, Xie W, Zhang X, Zhou J, Chan F. Interplay between orphan nuclear receptors and androgen receptor-dependent or-independent growth signalings in prostate cancer. Mol Aspects Med. 2021; 78:100921.
4. Xu Z, Ma T, Zhou J, Gao W, Li Y, Yu S, Wang Y, Chan F. Nuclear receptor ERRα contributes to castration-resistant growth of prostate cancer via its regulation of intratumoral androgen biosynthesis. Theranostics. 2020; 10(9):4201-4216.
5. Gao W#, Xiao F, Wang X, Chen T. Artemisinin induces apoptosis of A549 cells dominantly via a ROS-mediated positive feedback amplification activation loop among caspase-9, 3 and 8. Apoptosis. 2013; 18 (10): 1201-1213.
6. Xiao F, Gao W#, Wang X, Chen T. Amplification activation loop between caspase-8 and -9 dominates artemisinin-induced apoptosis of ASTC-a-1 cells. Apoptosis. 2012; 17(6):600-11.
四、 奖励
2015-2018 Postgraduate studentships, The Chinese University of Hong Kong.