科研成果

最新高水平论文

作者:生命科学学院发布时间:2022年01月16日 16:54

2022

1.        Zhan Y, Shi J, Xiao Y, Zhou F, Wang H, Xu H, Li Z, Yang S, Cai D, Chen S. (2022) Multilevel metabolic engineering of Bacillus licheniformis for de novo biosynthesis of 2-phenylethanol. Metabolic Engineering doi.org/10.1016/j.ymben.2022.01.007

2.        Li S, Yang X, Huang H, Qiao R, Jenks MA, Zhao H, Lü S. (2022) Arabidopsis ACYL-ACTIVATING ENZYME 9 (AAE9) encoding an isobutyl-CoA synthetase is a key factor connecting branched-chain amino acid catabolism with iso-branched wax biosynthesis. New Phytologist doi.org/10.1111/nph.17941

2021

1.        Zhan Y, Xu Y, Lu X, Zhou F, Zheng P, Wang D, Cai D, Yang S, Chen S. (2021) Metabolic engineering of Bacillus licheniformis for sustainable production of isobutanol. ACS Sustainable Chemistry & Engineering 9, 51.

2.        Zhou P, Wang L, Liu H, Li C, Li Z, Wang J, Tan X. (2021) CyanoOmicsDB: an integrated omics database for functional genomic analysis of cyanobacteria. Nucleic Acids Research 50, 758–764.

3.        Hu YH, Wang Y, Wang F, Dong YM, Jiang WL, Wang YP, Zhong X, Ma LX. (2021) SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association. Cellular & Molecular Immunology 18, 1708–1717.

4.        Wang L, Qin W, Xu W, Huang F, Xie X, Wang F, Ma L, Zhang C. (2021) Bacteria-mediated tumor therapy via photothermally-programmed cytolysin A expression. Small 17, e2102932.

5.        Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Guillen VS, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH,  Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. (2021) Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America 118, e2101657118.

6.        Chen W, Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S. (2021) The SESAME complex regulates cell senescence through the generation of acetyl-CoA. Nature Metabolism 3, 983–1000.

7.        Qiao B, Xu J, Yin W, Xin W, Ma L, Qiao J, Liu Y. (2021) “Aptamer-locker” DNA coupling with CRISPR/Cas12a-guided biosensing for high-efficiency melamine analysis. Biosensors and Bioelectronics 183, 113233.

8.        Chen CC, Han X, Li X, Jiang P, Niu D, Ma L, Liu W, Li S, Qu Y, Hu H, Min J, Yang Y, Zhang L, Zeng W, Huang J, Dai L, Guo RT. (2021) General features to enhance enzymatic activity of poly (ethylene terephthalate) hydrolysis. Nature Catalysis 4, 425–430.

9.        Xu L, Xu S, Sun L, Zhang Y, Luo J, Bock R, Zhang J. (2021). Synergistic action of the gut microbiota in environmental RNA interference in a leaf beetle. Microbiome 9, 1–14.

10.    Jia Y, Jin S, Hu K, Geng L, Han C, Kang R, Pang Y, Ling E, Tan EK, Pan Y, Liu W. (2021) Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature Communications 12, 1–12.

11.    Zhang S, Yu X, Zhang Y, Xue X, Yu Q, Zha Z, Gogol M, Workman JL, Li, S. (2021). Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation. Nature Communications 12, 1–15.

12.    Wang F, Yang J, He R, Yu X, Chen S, Liu Y, Wang L, Li A, Liu L, Zhai C, Ma L. (2021) PfAgo-based detection of SARS-CoV-2. Biosensors and Bioelectronics 177, 112932.

13.    Liu Y, Li, W, Jiang X, Wang Y, Zhang Z, Liu Q, He R, Chen Q, Yang J, Wang L, Wang F, Ma L. (2021) A programmable omnipotent Argonaute nuclease from mesophilic bacteria Kurthia massiliensis. Nucleic Acids Research 49, 1597–1608.

2020

1.        Chen CC, Dai L, Ma L, Guo RT. (2020). Enzymatic degradation of plant biomass and synthetic polymers. Nature Reviews Chemistry 4 114–126.

2.        Ouyang M, Li X, Zhang J, Feng P, Pu H, Kong L, Bai Z, Rong L, Xu X, Chi W, Wang Q, Chen F, Lu C, Shen J, Zhang L. (2020) Liquid-liquid phase transition drives intra-chloroplast cargo sorting. Cell 180, 1144–1159.

3.        Chen CC, Zhang L, Yu X, Ma L, Ko T P, Guo RT. (2020). Versatile cis-isoprenyl diphosphate synthase superfamily members in catalyzing carbon-carbon bond formation. ACS Catalysis 10, 4717–4725.

4.        Chen CC, Malwal SR, Han X, Liu W, Ma L, Zhai C, Dai L, Huang JW, Shillo, A, Desai J, Ma X, Zhang Y, Guo RT, Oldfield, E. (2020) Terpene cyclases and prenyltransferases: structures and mechanisms of action. ACS Catalysis 11, 290–303.

5.        Wang F, Zhao J, Li Q, Yang J, Li R, Min J, Yu X, Zheng GW, Yu HL, Zhai C, Acevedo-Rocha CG, Ma L, Li A. (2020) One-pot biocatalytic route from cycloalkanes to α, ω‐dicarboxylic acids by designed Escherichia coli consortia. Nature Communications 11, 1–10.

6.        Zhang L, Xie Z, Liu Z, Zhou S, Ma L, Liu W, Huang J W, Ko TP, Li X, Hu Y, Min J, Yu X, Guo RT, Chen CC. (2020) Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase. Nature Communications 11, 2676.

7.        Zhang Z, Li Q, Wang F, Li R, Yu X, Kang L, Zhao J, Li, A. (2020) One-pot biosynthesis of 1, 6-hexanediol from cyclohexane by de novo designed cascade biocatalysis. Green Chemistry 22, 7476–7483.

8.        Chen CC, Zhang L, Yu X, Ma L, Ko TP, Guo RT. (2020) Versatile cis-isoprenyl diphosphate synthase superfamily members in catalyzing carbon-carbon bond formation. ACS Catalysis 10, 4717–4725.

9.        Li A, Acevedo‐Rocha CG, D'Amore L, Chen J, Peng Y, Garcia‐Borràs M, Gao C, Zhu J, Rickerby H, Osuna S, Zhou J, Reetz MT. (2020). Regio‐and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants. Angewandte Chemie International Edition 59, 12499–12505.

10.    Zhang C, Qin WJ, Bai XF, Zhang XZ. (2020). Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy. Nano Today 35, 100960.

11.    Qu G, Li A, Acevedo‐Rocha CG, Sun Z, Reetz MT. (2020) The crucial role of methodology development in directed evolution of selective enzymes. Angewandte Chemie International Edition 59, 13204–13231.

2019

1.        Li A, Qu G, Sun Z, Reetz MT. (2019) Statistical analysis of the benefits of focused saturation mutagenesis in directed evolution based on reduced amino acid alphabets. ACS Catalysis 9, 7769–7778.

2.        Yang Y, Li L, Yuan L, Zhou X, Duan J, Xiao H, Cai N, Han S, Ma X, Liu W, Chen CC, Wang L, Li X, Chen J, Kang N, Chen J, Shen Z., Malwal S R, Liu W, Shi Y, Oldfield E, Guo RT, Zhang Y. (2019) A structural change in butyrophilin upon phosphoantigen binding underlies phosphoantigen-mediated Vγ9Vδ2 T cell activation. Immunity 50, 1043–1053.

3.        Li RJ, Li, LM, Liu XL, Kim JC, Jenks M A, Lü S. (2019). Diurnal regulation of plant epidermal wax synthesis through antagonistic roles of the transcription factors SPL9 and DEWAX. The Plant Cell 31, 2711–2733.

4.        Fan W, Lu J, Pan C, Tan M, Lin Q, Liu W, Li D, Wang L, Hu L, Wang L, Chen C, Wu A, Yu X, Ruan J, Yu J, Hu S, Yan X, Lü S, Cui P. (2019). Sequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci. Nature Communications 10, 1–11.

5.        Lu Z, Yang, S, Yuan, X, Shi Y, Ouyang, L, Jiang S, Yi L, Zhang, G. (2019). CRISPR-assisted multi-dimensional regulation for fine-tuning gene expression in Bacillus subtilis. Nucleic Acids Research 47, e40.

6.        Mei Q, Xu C, Gogol M, Tang J, Chen W, Yu X, Workman JL, Li S. (2019). Set1-catalyzed H3K4 trimethylation antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and chronological life span. Nucleic Acids Research 47, 3434–3449.

7.        Ma R, Wu Y, Zhai Y, Hu B, Ma W, Yang W, Yu Q, Chen Z, Workman JL, Yu X, Li S. (2019) Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT-NAD+-SIRT1 pathway. Nucleic Acids Research 47, 11132–11150.

8.        Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Amy E. Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK. (2019) Insights into the pathogenesis of catecholaminergic polymorphic ventricular tachycardia from engineered human heart tissue. Circulation 140, 390–404.

9.        Xia J, Yang Y, Liu CG, Yang S, Bai FW. (2019) Engineering Zymomonas mobilis for robust cellulosic ethanol production. Trends in Biotechnology 37, 960–972.

10.    Peng B, Ma CL, Zhang PQ, Wu CQ, Wang ZW, Li AT, ... & Yang B. (2019). An effective hybrid strategy for converting rice straw to furoic acid by tandem catalysis via Sn-sepiolite combined with recombinant E. coli whole cells harboring horse liver alcohol dehydrogenase. Green Chemistry 21, 5914–5923.

11.    Zheng Y, Han J, Wang B, Hu X, Li, R, Shen W, ... & Peng W. (2019). Characterization and repurposing of the endogenous Type IF CRISPR-Cas system of Zymomonas mobilis for genome engineering. Nucleic Acids Research 47, 11461–11475.

12.    Chen CC, Hu X, Tang X, Yang Y, Ko T P, Gao J, ... & Guo RT. (2018) The crystal structure of a class of cyclases that catalyze the cope rearrangement. Angewandte Chemie International Edition 130, 15280–15284.

13.    Zhou H, Wang B, Wang, F, Yu X, Ma L, Li A, Reetz MT. (2019) Chemo‐and regioselective dihydroxylation of benzene to hydroquinone enabled by engineered cytochrome P450 monooxygenase. Angewandte Chemie International Edition 131, 774–778.