作者:生命科学学院发布时间:2023年05月15日 17:27


1. Wang Y, Min J, Deng X, Feng T, Hu H, Guo X, Cheng Y, Xie B, Yang Y, Chen CC, Guo RT, Dong C, Zhou HB. (2023) Discovery of novel covalent selective estrogen receptor degraders against endocrine-resistant breast cancer. Acta Pharmaceutica Sinica B doi.org/10.1016/j.apsb.2023.05.005

2. Jiang M, Wu Y, He P, Hu S, Li Q, Chen S. (2023) Assembled denitrifying consortia for efficient nitrate removal under low-COD/N conditions. Chemical Engineering Journal 460, 141655.

3. Liu W, Wang J, Comte-Miserez V, Zhang M, Yu X, Chen Q, Jessen HJ, Mayer A, Wu S, Ye S. (2023) Cryo-EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit. The EMBO Journal doi.org/10.15252/embj.2022113320

4. Yang Y, Min J, Xue T, Jiang P, Liu X, Peng R, Huang JW, Qu Y, Li X, Ma N, Tsai FC, Dai L, Zhang Q, Liu Y, Chen CC, Guo RT. (2023) Complete bioegradation of poly(butylene adipate-co-terephthalate) via engineered cutinases. Nature Communications 14, 1645.

5. Wu Y, Tang L, Huang H, Yu Q, Hu B, Wang G, Ge F, Yin T, Li S, Yu X. (2023) Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence. Nature Communications 14, 1323.

6. Li X, Mei Q, Yu Q, Wang M, He F, Xiao D, Liu H, Ge F, Yu X, Li S. (2023) The TORC1 activates Rpd3L complex to deacetylate Ino80 and H2A.Z and repress autophagy. Science Advances 9, eade8312.

7. Zhang Z, Fang L, Wang F, Deng Y, Jiang Z, Li A. (2023) Transforming inert cycloalkanes into α,ω-Diamines by designed enzymatic cascade catalysis. Angewandte Chemie International Edition 62, e202215935.

8. Huang H, Yang X, Zheng M, Chen Z, Yang Z, Wu P, Jenks MA, Wang G, Feng T, Liu L, Yang P, Lü S, Zhao H. (2023) An ancestral role for 3-KETOACYL-COA SYNTHASE3 as a negative regulator of plant cuticular wax synthesis. The Plant Cell doi.org/10.1093/plcell/koad051

9. Yan J, Liu F, Guan Z, Yan X, Jin X, Wang Q, Wang Z, Yan J, Zhang D, Liu Z, Wu S, Yin P. (2023) Structural insights into DNA N6-adenine methylation by the MTA1 complex. Cell Discovery 9, 8.

10. Zhang S, Wu CQ, Ma C, Li L, He YC. (2023) Transformation of bread waste into 2,5-furandimethanol via an efficient chemoenzymatic approach in a benign reaction system. Bioresource Technology 371, 128579

11. Di JH, Li Q, Ma CL, He YC. (2023) An efficient and sustainable furfurylamine production from biomass-derived furfural by a robust mutant co-transaminase biocatalyst. Bioresource Technology 369, 128425.

12. Tang Z, Li Q, Di J, Ma CL, He YC. (2023) An efficient chemoenzymatic cascade strategy for transforming biomass into furfurylamine with lobster shell-based chemocatalyst and mutated ω-transaminase biocatalyst in methyl isobutyl ketone-water. Bioresource Technology 369, 128424.

13. Li A, Wang Q, Song X, Zhang X,   Huang JW, Chen CC, Guo RT, Wang B, Reetz MT. (2023) Engineering of a P450‐based Kemp eliminase with a new mechanism. Chinese Journal of Catalysis 47, 191–199.    

14. Zhang X, Shen P, Zhao J, Chen Y, Li X, Huang JW, Zhang L, Li Q, Gao C, Xing Q, Chen CC, Guo RT, Li A. (2023) Rationally controlling selective steroid hydroxylation via scaffold sampling of a P450 family. ACS Catalysis 13, 1280–1289.

15. Hu R, Gong A, Liao L, Zheng Y, Liu X. Wu P, Li F, Yu H, Zhao J, Ye L, Wang B, Li A. (2023) Biocatalytic aminohydroxylation of styrenes for efficient synthesis of enantiopure β-amino alcohols. Chinese Journal of Catalysis 44171–178.

16. Li J, Liu Z, Wang Y, Yu C, Wang F. (2023) Microplastic accelerate the phosphorus-related metabolism of bacteria to promote the decomposition of methylphosphonate to methane. Science of the Total Environment 858, 160020.

17. Liu J, Li B, Li Z, Yang F, Chen B, Chen J, Li H, Jiang Z. (2023) Deciphering the alkaline stable mechanism of bacterial laccase from Bacillus pumilus by molecular dynamics simulation can improve the decolorization of textile dyes. Journal of Hazardous Materials 443, 130370

18. Wu M, Zhang Q, Dong Y, Wang Z, Zhan W, Ke Z, Li S, He L, Ruf S, Bock R, Zhang J. (2023) Transplastomic tomatoes expressing double-stranded RNA against a conserved gene are efficiently protected from multiple spider mites. New Physologist 237, 13631373.

19. Ren D, Cheng Y, Xu W, Qin W, Hao T, Wang F, Hu Y, Ma L, Zhang C. (2023) Copper-based metal-organic framework induces NO generation for synergistic tumor therapy and antimetastasis activity. Small 19, 2205772.


1. He N, Zhou J, Bimai O, Oltmanns J, Ravanat JL, Velours C, Schünemann V, Fontecave M, Golinelli-Pimpaneau B. (2022) A subclass of archaeal U8-tRNA sulfurases requires a [4Fe–4S] cluster for catalysis. Nucleic Acids Research 50, 12969–12978.

2. Chen Q, Li BB, Zhang L, Chen XR, Zhu XX, Chen FF, Shi M, Chen CC, Yang Y, Guo RT, Liu W, Xu JH, Zheng GW. (2022) Engineered imine reductase for larotrectinib intermediate manufacture. ACS Catalysis 23, 14795–14803

3. Wu L, An J, Jing X, Chen CC, Dai L, Xu Y, Liu W, Guo RT, Nie Y. (2022) Molecular insights into the regioselectivity of the Fe(II)/2-ketoglutarate-dependent dioxygenase-catalyzed C–H hydroxylation of amino acids. ACS Catalysis 19, 11586–11596.

4. He F, Yu Q, Wang M, Wang R, Gong X, Ge F, Yu X, Li S. (2022) SESAME-catalyzed H3T11 phosphorylation inhibits Dot1-catalyzed H3K79me3 to regulate autophagy and telomere silencing. Nature Communications 13, 7526.

5. Qian Y, Wang J, Yang L, Liu Y, Wang L, Liu W, Lin Y, Yang H, Ma L, Ye S, Wu S, Qiao A. (2022) Activation and signaling mechanism revealed by GPR119-Gs complex structures. Nature Communications 13, 7033.

6. Zhang M, Song J, Xiao J, Jin J, Nomura CT, Chen S, Wang Q. (2022) Engineered multiple translation initiation sites: a novel tool to enhance protein production in Bacillus licheniformis and other industrially relevant bacteria. Nucleic Acids Research 50, 11979–11990.

7. Su N, Zhu A, Tao X, Ding ZJ, Chang S, Ye F, Zhang Y, Zhao C, Chen Q, Wang J, Zhou CY, Guo Y, Jiao S, Zhang S, Wen H, Ma L, Ye S, Zheng SJ, Yang F, Wu S, Guo J. (2022) Structures and mechanisms of the Arabidopsis auxin transporter PIN3. Nature 609, 616–621

8. Qi Yu, Gong X, Tong Y, Wang M, Duan K, Zhang X, Ge F, Yu X, Li S. (2022) Phosphorylation of Jhd2 by the Ras-cAMP-PKA(Tpk2) pathway regulates histone modifications and autophagy. Nature Communications 13, 5675.

9. Huang J, Dai W, Xiao D, Xiong Q, Liu C, Hu J, Ge F, Yu X, Li S. (2022) Acetylation-dependent SAGA complex dimerization promotes nucleosome acetylation and gene transcription. Nature Structural & Molecular Biology 29, 261–273.

10. Wang Y, Guan Z, Wang C, Nie Y, Chen Y, Qian Z, Cui Y, Xu H, Wang Q, Zhao F, Zhang D, Tao P, Sun M, Yin P, Jin S, Wu S, Zou T. (2022) Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism. Nature Microbiology 7, 1480–1489.

11. Li L, Wan Z, Wang R, Zhao Y, Ye Y, Yang P, Qi Y, Jiang W, Cai L, Zhang D. (2022) Generation of high-performance human cardiomyocytes and engineered heart tissues from extended pluripotent stem cells. Cell Discovery 8, 105.

12. Mao Z, Xiao H, Shen P, Yang Y, Xue J, Yang Y, Shang Y, Zhang L, Li X, Zhang Y, Du Y, Chen CC, Guo RT, Zhang Y. (2022) KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discovery 8, 5.

13. Cheng Y, Wang C, Wang H, Zhang Z, Yang X, Dong Y, Ma L, Luo J. (2022) Combination of an autophagy inhibitor with immunoadjuvants and an anti-PD-L1 antibody in multifunctional nanoparticles for enhanced breast cancer immunotherapy. BMC Medicine 20, 411.

14. Gong L, Zha J, Pan, L, Ma, C, He Y. (2022). Highly efficient conversion of sunflower stalk-hydrolysate to furfural by sunflower stalk residue-derived carbonaceous solid acid in deep eutectic solvent/organic solvent system. Bioresource Technology 351, 126945.

15. Yan X, Wang X, Yang Y, Wang Z, Zhang H, He Q, Yang S. (2022) Cysteine supplementation enhanced inhibitor tolerance of Zymomonas mobilis for economic lignocellulosic bioethanol production. Bioresource Technology 349, 126878.

16. Li Q, Ma C, Di J, Ni J, He Y. (2022). Catalytic valorization of biomass for furfuryl alcohol by novel deep eutectic solvent-silica chemocatalyst and newly constructed reductase biocatalyst. Bioresource Technology 347, 126376.

17. Ran Q, Li H, Liu J, Huang M, Zhou Y, Zhang L, Gu L, Jiang Z. (2022) An effective strategy for improving the specific activity and saccharification efficiency of cellulase by pre-incubation with phenolic acids. Bioresource Technology 346, 126644

18. Li H, Xiao W, Liu J, Ran Q, Wang R, Yu C, Zhang X, Song H, Jiang Z. (2022) Combination strategy of laccase pretreatment and rhamnolipid addition enhance ethanol production in simultaneous saccharification and fermentation of corn stover. Bioresource Technology 345, 126414

19. Zhang SL, Ma CL, Li Q, Li Q, He YC. (2022) Efficient chemoenzymatic valorization of biobased D-fructose into 2,5-bis(hydroxymethyl)furan with deep eutectic solvent lactic acid: Betaine and Pseudomonas putida S12 whole cells. Bioresource Technology 344, 126299.

20. Wu M, Di J, Gong L, He YC, Ma C, Deng Y. (2022). Enhanced adipic acid production from sugarcane bagasse by a rapid room temperature pretreatment. Chemical Engineering Journal 452, 139320.

21. Jiang M, Li Q, Hu S, He P, Chen Y, Cai D, Wu Y, Chen S. (2022) Enhanced aerobic denitrification performance with Bacillus licheniformis via secreting lipopeptide biosurfactant lichenysin. Chemical Engineering Journal 434, 134686.

22. Wang T, Dong D, Chen T, Zhu J, Wang S, Wen W, Zhang X, Tang H, Liang J, Wang S, Xiong H. (2022) Acidity-responsive cascade nanoreactor based on metal-nanozyme and glucose oxidase combination for starving and photothermal-enhanced chemodynamic antibacterial therapy. Chemical Engineering Journal 446, 137172

23. Pei J, Cai L, Wang F, Xu C, Pei S, Guo H, Sun X, Chun J, Cong X, Zhu W, Zheng Z, Chen X. (2022) LPA2 contributes to vascular endothelium homeostasis and cardiac remodeling after myocardial infarction. Circulation Research 131, 388–403

24. Qi Y, Ye Y, Wang R, Yu S, Zhang Y, Lv J, Jin W, Xia S, Jiang W, Li Y, Zhang D. (2022) Mitochondrial dysfunction by TFAM depletion disrupts self-renewal and lineage differentiation of human PSCs by affecting cell proliferation and YAP response. Redox Biology 50, 102248.

25. Wang J, Liu Q, Gong J, Wan Z, Zhou J, Chang C, Zhang D. (2022) Micropatterned hydrogels with highly ordered cellulose nanocrystals for visually monitoring cardiomyocytes. Small 18, 202202235

26. Li H, Yang Y, Hu Y, Chen CC, Huang JW, Min J, Dai L, Guo RT. (2022) Structural analysis and engineering of aldo-keto reductase from glyphosate-resistant Echinochloa colonaJournal of Hazardous Materials 436, 129191.

27. Li Q, Zhang Z, Zhao J, Li A. (2022) Recent advances in the sustainable production of α, ω-C6 bifunctional compounds enabled by chemo-/biocatalysts. Green Chemistry 24, 4270–4303

28. Li W, Liu Y, He R, Wang L, Wang Y, Zeng W, Zhang Z, Wang F, Ma L. (2022) A programmable pAgo nuclease with RNA target preference from the psychrotolerant bacterium Mucilaginibacter paludis. Nucleic Acids Research 50, 5226–5238.

29. Sun Z, Wang Y, Song Z, Zhang H, Wang Y, Liu K, Ma M, Wang P, Fang Y, Cai D, Li G, Fang Y. (2022) DNA methylation in transposable elements buffers the connection between three-dimensional chromatin organization and gene transcription upon rice genome duplication. Journal of Advanced Research 42, 41–53.

30. Dong Y, Wu M, Zhang Q, Fu J, Loiacono FV, Yang Y, Wang Z, Li S, Chang L, Bock R, Zhang J. (2022) Control of a sap-sucking insect pest by plastid-mediated RNA interference. Molecular Plant 15, 1176–1191. 

31. Wu M, Dong Y, Zhang Q, Li S, Chang L, Loiacono FV, Ruf S, Zhang J, Bock R. (2022) Efficient control of western flower thrips by plastid-mediated RNA interference. Proceedings of the National Academy of Sciences of the United States of America 119, e2120081119.

32. Feng T, Wu P, Gao H, Kosma DK, Jenks MA, Lü S. (2022) Natural variation in root suberization is associated with local environment in Arabidopsis thalianaNew Phytologist 236, 385–398.

33. Li S, Yang X, Huang H, Qiao R, Jenks MA, Zhao H, Lü S. (2022) Arabidopsis ACYL-ACTIVATING ENZYME 9 (AAE9) encoding an isobutyl-CoA synthetase is a key factor connecting branched-chain amino acid catabolism with iso-branched wax biosynthesis. New Phytologist 233, 2458–2470.

34. Zhang S, Liu, Y; Ma Y; Wang H; Zhao Y; Kuntner M, Li D. (2022) Male spiders avoid sexual cannibalism with a catapult mechanism. Current Biology 32, 354–355.

35. Qin W, Xu W, Wang L, Ren D, Cheng Y, Song W, Jiang T, Ma L, Zhang C. (2022) Bacteria-elicited specific thrombosis utilizing acid-induced cytolysin A expression to enable potent tumor therapy. Advanced Science 9, 202105086.

36. Li Y, Wang Y, Wang R, Yan X, Wang J, Wang X, Chen S, Bai F, He Q, Yang S. (2022) Metabolic engineering of Zymomonas mobilis for continuous co-production of bioethanol and poly-3-hydroxybutyrate (PHB). Green Chemistry 24, 2588–2601.

37. Peng Y, Gao C, Zhang Z, Wu S, Zhao J, Li A. (2022) A chemoenzymatic strategy for the synthesis of steroid drugs enabled by P450 monooxygenase-mediated steroidal core modification. ACS Catalysis 12, 2907–2914.

38. Zeng W, Li X, Yang Y, Min J, Huang JW, Liu W, Niu D, Yang X, Han X, Zhang L, Dai L, Chen CC, Guo RT. (2022) Substrate-binding mode of a thermophilic PET hydrolase and engineering the enzyme to enhance the hydrolytic efficacy. ACS Catalysis 12, 3033–3040.

39. Chen CC, Dai M, Zhang L, Zhao J, Zeng W, Shi M, Huang JW, Liu W, Guo RT, Li A. (2022) Molecular basis for a toluene monooxygenase to govern substrate selectivity. ACS Catalysis 12, 2831–2839.


1. Li Q, Di J, Liao X, Ni J, Li Q, He YC, Ma C (2021) Exploration of benign deep eutectic solvent-water systems for the highly efficient production of furfurylamine from sugarcane bagasse via chemoenzymatic cascade catalysis. Green Chemistry 23, 8154-8168.

2. Zhou P, Wang L, Liu H, Li C, Li Z, Wang J, Tan X. (2021) CyanoOmicsDB: an integrated omics database for functional genomic analysis of cyanobacteria. Nucleic Acids Research 50, 758–764.

3. Hu YH, Wang Y, Wang F, Dong YM, Jiang WL, Wang YP, Zhong X, Ma LX. (2021) SPOP negatively regulates Toll-like receptor-induced inflammation by disrupting MyD88 self-association. Cellular & Molecular Immunology 18, 1708–1717.

4. Wang L, Qin W, Xu W, Huang F, Xie X, Wang F, Ma L, Zhang C. (2021) Bacteria-mediated tumor therapy via photothermally-programmed cytolysin A expression. Small 17, e2102932.

5. Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Guillen VS, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH,  Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. (2021) Dual-mechanism estrogen receptor inhibitors. Proceedings of the National Academy of Sciences of the United States of America 118, e2101657118.

6. Chen W, Chen W, Yu X, Wu Y, Tang J, Yu Q, Lv X, Zha Z, Hu B, Li X, Chen J, Ma L, Workman JL, Li S. (2021) The SESAME complex regulates cell senescence through the generation of acetyl-CoA. Nature Metabolism 3, 983–1000.

7. Qiao B, Xu J, Yin W, Xin W, Ma L, Qiao J, Liu Y. (2021) “Aptamer-locker” DNA coupling with CRISPR/Cas12a-guided biosensing for high-efficiency melamine analysis. Biosensors and Bioelectronics 183, 113233.

8. Chen CC, Han X, Li X, Jiang P, Niu D, Ma L, Liu W, Li S, Qu Y, Hu H, Min J, Yang Y, Zhang L, Zeng W, Huang J, Dai L, Guo RT. (2021) General features to enhance enzymatic activity of poly (ethylene terephthalate) hydrolysis. Nature Catalysis 4, 425–430.

9. Xu L, Xu S, Sun L, Zhang Y, Luo J, Bock R, Zhang J. (2021). Synergistic action of the gut microbiota in environmental RNA interference in a leaf beetle. Microbiome 9, 1–14.

10. Jia Y, Jin S, Hu K, Geng L, Han C, Kang R, Pang Y, Ling E, Tan EK, Pan Y, Liu W. (2021) Gut microbiome modulates Drosophila aggression through octopamine signaling. Nature Communications 12, 1–12.

11. Zhang S, Yu X, Zhang Y, Xue X, Yu Q, Zha Z, Gogol M, Workman JL, Li, S. (2021). Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation. Nature Communications 12, 1–15.

12. Wang F, Yang J, He R, Yu X, Chen S, Liu Y, Wang L, Li A, Liu L, Zhai C, Ma L. (2021) PfAgo-based detection of SARS-CoV-2. Biosensors and Bioelectronics 177, 112932.

13. Liu Y, Li, W, Jiang X, Wang Y, Zhang Z, Liu Q, He R, Chen Q, Yang J, Wang L, Wang F, Ma L. (2021) A programmable omnipotent Argonaute nuclease from mesophilic bacteria Kurthia massiliensisNucleic Acids Research 49, 1597–1608.


1. Chen CC, Dai L, Ma L, Guo RT. (2020). Enzymatic degradation of plant biomass and synthetic polymers. Nature Reviews Chemistry 4 114–126.

2. Ouyang M, Li X, Zhang J, Feng P, Pu H, Kong L, Bai Z, Rong L, Xu X, Chi W, Wang Q, Chen F, Lu C, Shen J, Zhang L. (2020) Liquid-liquid phase transition drives intra-chloroplast cargo sorting. Cell 180, 1144–1159.

3. Chen CC, Zhang L, Yu X, Ma L, Ko T P, Guo RT. (2020). Versatile cis-isoprenyl diphosphate synthase superfamily members in catalyzing carbon-carbon bond formation. ACS Catalysis 10, 4717–4725.

4. Chen CC, Malwal SR, Han X, Liu W, Ma L, Zhai C, Dai L, Huang JW, Shillo, A, Desai J, Ma X, Zhang Y, Guo RT, Oldfield, E. (2020) Terpene cyclases and prenyltransferases: structures and mechanisms of action. ACS Catalysis 11, 290–303.

5. Wang F, Zhao J, Li Q, Yang J, Li R, Min J, Yu X, Zheng GW, Yu HL, Zhai C, Acevedo-Rocha CG, Ma L, Li A. (2020) One-pot biocatalytic route from cycloalkanes to α, ω‐dicarboxylic acids by designed Escherichia coli consortia. Nature Communications 11, 1–10.

6. Zhang L, Xie Z, Liu Z, Zhou S, Ma L, Liu W, Huang J W, Ko TP, Li X, Hu Y, Min J, Yu X, Guo RT, Chen CC. (2020) Structural insight into the electron transfer pathway of a self-sufficient P450 monooxygenase. Nature Communications 11, 2676.

7. Zhang Z, Li Q, Wang F, Li R, Yu X, Kang L, Zhao J, Li, A. (2020) One-pot biosynthesis of 1, 6-hexanediol from cyclohexane by de novo designed cascade biocatalysis. Green Chemistry 22, 7476–7483.

8. Chen CC, Zhang L, Yu X, Ma L, Ko TP, Guo RT. (2020) Versatile cis-isoprenyl diphosphate synthase superfamily members in catalyzing carbon-carbon bond formation. ACS Catalysis 10, 4717–4725.

9. Li A, Acevedo‐Rocha CG, D'Amore L, Chen J, Peng Y, Garcia‐Borràs M, Gao C, Zhu J, Rickerby H, Osuna S, Zhou J, Reetz MT. (2020). Regio‐and stereoselective steroid hydroxylation at C7 by cytochrome P450 monooxygenase mutants. Angewandte Chemie International Edition 59, 12499–12505.

10. Zhang C, Qin WJ, Bai XF, Zhang XZ. (2020). Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy. Nano Today 35, 100960.

11. Qu G, Li A, Acevedo‐Rocha CG, Sun Z, Reetz MT. (2020) The crucial role of methodology development in directed evolution of selective enzymes. Angewandte Chemie International Edition 59, 13204–13231.


1. Li A, Qu G, Sun Z, Reetz MT. (2019) Statistical analysis of the benefits of focused saturation mutagenesis in directed evolution based on reduced amino acid alphabets. ACS Catalysis 9, 7769–7778.

2. Yang Y, Li L, Yuan L, Zhou X, Duan J, Xiao H, Cai N, Han S, Ma X, Liu W, Chen CC, Wang L, Li X, Chen J, Kang N, Chen J, Shen Z., Malwal S R, Liu W, Shi Y, Oldfield E, Guo RT, Zhang Y. (2019) A structural change in butyrophilin upon phosphoantigen binding underlies phosphoantigen-mediated Vγ9Vδ2 T cell activation. Immunity 50, 1043–1053

3. Li RJ, Li, LM, Liu XL, Kim JC, Jenks M A, Lü S. (2019). Diurnal regulation of plant epidermal wax synthesis through antagonistic roles of the transcription factors SPL9 and DEWAX. The Plant Cell 31, 2711–2733.

4. Fan W, Lu J, Pan C, Tan M, Lin Q, Liu W, Li D, Wang L, Hu L, Wang L, Chen C, Wu A, Yu X, Ruan J, Yu J, Hu S, Yan X, Lü S, Cui P. (2019). Sequencing of Chinese castor lines reveals genetic signatures of selection and yield-associated loci. Nature Communications 10, 1–11.

5. Lu Z, Yang, S, Yuan, X, Shi Y, Ouyang, L, Jiang S, Yi L, Zhang, G. (2019). CRISPR-assisted multi-dimensional regulation for fine-tuning gene expression in Bacillus subtilisNucleic Acids Research 47, e40.

6. Mei Q, Xu C, Gogol M, Tang J, Chen W, Yu X, Workman JL, Li S. (2019). Set1-catalyzed H3K4 trimethylation antagonizes the HIR/Asf1/Rtt106 repressor complex to promote histone gene expression and chronological life span. Nucleic Acids Research 47, 3434–3449.

7. Ma R, Wu Y, Zhai Y, Hu B, Ma W, Yang W, Yu Q, Chen Z, Workman JL, Yu X, Li S. (2019) Exogenous pyruvate represses histone gene expression and inhibits cancer cell proliferation via the NAMPT-NAD+-SIRT1 pathway. Nucleic Acids Research 47, 11132–11150.

8. Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Amy E. Roberts AE, Kleber AG, Abrams DJ, Pu WT, Parker KK. (2019) Insights into the pathogenesis of catecholaminergic polymorphic ventricular tachycardia from engineered human heart tissue. Circulation 140, 390–404.

9. Xia J, Yang Y, Liu CG, Yang S, Bai FW. (2019) Engineering Zymomonas mobilis for robust cellulosic ethanol production. Trends in Biotechnology 37, 960–972.

10. Peng B, Ma CL, Zhang PQ, Wu CQ, Wang ZW, Li AT, ... & Yang B. (2019). An effective hybrid strategy for converting rice straw to furoic acid by tandem catalysis via Sn-sepiolite combined with recombinant E. coli whole cells harboring horse liver alcohol dehydrogenase. Green Chemistry 21, 5914–5923.

11. Zheng Y, Han J, Wang B, Hu X, Li, R, Shen W, ... & Peng W. (2019). Characterization and repurposing of the endogenous Type IF CRISPR-Cas system of Zymomonas mobilis for genome engineering. Nucleic Acids Research 47, 11461–11475.

12. Chen CC, Hu X, Tang X, Yang Y, Ko T P, Gao J, ... & Guo RT. (2018) The crystal structure of a class of cyclases that catalyze the cope rearrangement. Angewandte Chemie International Edition 130, 15280–15284.

13. Zhou H, Wang B, Wang, F, Yu X, Ma L, Li A, Reetz MT. (2019) Chemo‐and regioselective dihydroxylation of benzene to hydroquinone enabled by engineered cytochrome P450 monooxygenase. Angewandte Chemie International Edition 131, 774–778.