2025

1. Meng Li, Songli Zhou, Suqin Zhang, Xingyu Xie, Junqi Nie, Qi Wang, Lixin Ma, Yibin Cheng, Jingwen Luo. (2025) Transdermal delivery of CRISPR/Cas9-mediated melanoma gene therapy via polyamines-modified thermosensitive hydrogels. Journal of Nanobiotechnology. 23:441.

2. Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang. (2025) A Human Engineered Heart Tissue-Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin. Advanced Science. 28:e03173.

3. Longyu Wang, Xiaochen Xie, Fuyong Huang, Qiang Wei, Tianxin Cai, Na Yu, Shi Chen, Fei Wang, Wanping Chen, Chin-Yu Chen, Chunhua Li, Lixin Ma. (2025) An Engineered PfAgo with Wide Catalytic Temperature Range and Substrate Spectrum. Advanced Science. 14: e2416631.

4. Wenjing Dai, Qi Yu, Rui Ma, Zhu Zheng, Lingling Hong, Yuqing Qi, Fei He, Min Wang, Feng Ge, Xilan Yu, Shanshan Li. (2025) PKA plays a conserved role in regulating gene expression and metabolic adaptation by phosphorylating Rpd3/HDAC1. Nature Communications. 16: 4030

5. Yan Li, Xuelian Guo, Jiayi Song, Kun Xu, Tian Qin, Xianhua Zhang, Zhaojian Song , Yuchi He, Biaoming Zhang, Haitao Zhang, Haitao Li, Wenya Yuan. (2025) OsSPL14 and OsNF-YB9/YC8-12 subunits cooperate to enhance grain appearance quality through promotingWaxyandPDIL1-1expression in rice. Plant Communications. 2:101348.

6. Suqin Zhang, Meng Li, Jingyi Zeng, Songli Zhou, Feifan Yue, Zhaoyi Chen, Lixin Ma, Yang Wang, Fei Wang, Jingwen Luo. (2025) Somatostatin receptor-targeted polymeric nanoplatform for efficient CRISPR/Cas9 gene editing to enhance synergistic hepatocellular carcinoma therapy. Journal of Nanobiotechnology. https://doi.org/10.1186/s12951-025-03214-3.

7. Wenxue Jiang, Miao Wu, Zhou Gong, Linhua Han, Xiaoqi Cheng, Xiaoqin Tang, Xiaolong Yu, Xu Dong, Yibin Cheng, Lixin Ma, Qiong Xing. (2025) Structure-guided engineering of a Rieske-type aromatic dioxygenase for enhanced consumption of 3-phenylpropionic acid in Escherichia coli. Journal of Hazardous Materials. 491, 137954.

8. Xu Dong, Manli Xu, Miao Wu, Ying Wang, Xiaoqi Cheng, Wenxue Jiang, Dule Zheng, Ahmed Habiba Omar, Yibin Cheng , Aitao Li , Lixin Ma , Qiong Xing. (2025) Structural and catalytic insights into MhpB: A dioxygenase enzyme for degrading catecholic pollutants. Journal of Hazardous Materials. 488, 137431.

9. Xiaolong Zhang, Bin Feng, Yu Wang, Tingting Mu, Ming Zheng, Changbin Gao, Biaoming Zhang, Yan Li, Haitao Zhang, Wenya Yuan, Wei Hua, Haitao Li. (2025) Targeted disruption of five Bna.BRC1 homologs in rapeseed generates a highly branched germplasm for its multifunctional utilization. Plant Communications. 20:101319.

10. Feng Wang, Haijiang Xu, Chendi Zhang, Jialin Xue, Zhuang Li. (2025) Target DNA-induced filament formation and nuclease activation of SPARDA complex. Cell Research. https://doi.org/10.1038/s41422-025-01100-z.

11. Huanhuan Qi, Jing Wang Xin Wang, Kun Liang, Meicheng Ke, Xueqing Zheng, Wenbin Tang, Ziyun Chen, Yinggen Ke, Pingfang Yang, Fazhan Qiu, Feng Yu. (2025) ZmEREB180 modulates waterlogging tolerance in maize by regulating root development and antioxidant gene expression. Plant Biotechnology Journal. https://doi: 10.1111/pbi.70030.

12. Linliang Zhang, Yali Qin, Mingzhou Chen. (2025) Flavivirus NS₂A orchestrates reticulophagy to enhance viral pathogenicity. Autophagy 7, 1–2.

13. Lixin Kang, Haoran Li, Kexin Lin, Shen Hu, Song Liu, Yuben Qiao, Ying Wang, Aitao Li. (2025) Regioselectivity Switching in CYP107Pdh-Catalyzed VD3 Hydroxylation: A Structure-Guided Approach To Improve Calcidiol Production. ACS Catalysis 0, 15. DOI: 10.1021/acscatal.5c00444.

14. Fei Wang, Huiqi Sun, Di Deng, Yuanqing Wu, Jing Zhao, Qian Li, Aitao Li. (2025) Multidimensional engineering of Escherichia coli for efficient adipic acid synthesis from cyclohexane. Advanced Science 17:e2411938.

15. Affiliations expandDi Deng, Zhihui Jiang, Lixin Kang, Langxing Liao, Xiaodong Zhang, Yuben Qiao, Yang Zhou, Liulin Yang, Binju Wang, Aitao Li. (2025) An efficient catalytic route in haem peroxygenases mediated by O₂/small-molecule reductant pairs for sustainable applications. Nature Catalysis 8, 20–32.

16. Yunyun Yang, Yanling Li, Licheng Yao, Kexiang Dai, Xiaolong Fu, Aoyue Ge, Jian-Wen Huang, Rey-Ting Guo, Chun-Chi Chen. (2025) Structural Insights into the N–N Bond-Formation Mechanism of the Heme-Dependent Piperazate Synthase KtzT. ACS Catalysis 15, 1265–1273.

17. Siyu Li, Jian-Wen Huang, Jian Min, Hao Li, Meidan Ning, Shuyu Zhou, Yu Yang, Chun-Chi Chen & Rey-Ting Guo. (2025) Molecular insights into a distinct class of terpenoid cyclases. Nature Communications 16, 207.

18. Hongxun Gao, Yakun Fan, Xuwei He, Xiaogang Peng, Zhen Li, Yanxin Zheng, Shengbiao Ji, Longwu Ye, Aitao Li, Binju Wang, Jing Zhao. (2025) Mechanistic Insights into the Selective C–S Bond Formation by P450 TleB. ACS Catalysis 14, 10658–10669.

19. Shipeng Li, Xuanhao Zhang, Haodong Huang, Mou Yin, Matthew A. Jenks, Dylan K. Kosma, Pingfang Yang, Xianpeng Yang, Huayan Zhao, Shiyou Lü. (2025) Deciphering the core shunt mechanism in Arabidopsis cuticular wax biosynthesis and its role in plant environmental adaptation. Nature Plants 11, 165–175.

20. Yuxin Zhang, Chengjie Tu, Jianyang Bai, Xiayu Li, Ziyue Sun, Letian Xu. (2025) Metabolic enhancement contributed by horizontal gene transfer is essential for dietary specialization in leaf beetles. Proceedings of the National Academy of Sciences of the United States of America 122, e2415717122.