副教授

谈晓明

发布时间:2018-10-24    点击率:

 

 

姓  名: 谈晓明

电子邮件: tanxm2013@163.com

通讯地址: 湖北省武汉市武昌区友谊大道368号湖北大学生命科学学院

任职情况:现任湖北大学副教授、硕士研究生导师

研究领域:微生物遗传学与代谢工程

一、学习和工作简历

l 19999-20037月,湖北大学生命科学学院,本科

l 20039-20097月,中国科学院水生生物研究所,硕博连读

l 20097-20183月,中国科学院青岛生物能源与过程研究所工作,任助理研究员、副研究员

l 20175-201711月,德国弗莱堡大学,访问学者

l 20183-湖北大学生命科学学院工作,副教授

二、承担科研项目情况

曾主持国家自然科学基金青年基金、山东省自然科学基金、山东省科技发展计划、中国科学院重要方向项目、青年创新促进会与地方企业横向合作项目等多项科研项目。目前主持国家自然科学基金项目1项:

1. 国家自然科学基金面上项目(2019.1~2020.12):参与速生蓝细菌盐胁迫调控的非编码RNA的鉴定和功能表征。项目批准号:31871303

三、代表性论文(*通讯作者)

1. Tan X#, Hou S#, Song K, Georg J, Klähn S, Lu X* and Hess WR*. The primary transcriptome of the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973. Biotechnol biofuels. 2018;11:218.

2. Lou W#, Tan X#, Song K, Zhang S, Luan G, Li C and Lu X*. Single SNP in ATP Synthase Gene Significantly Improves Environmental Stress Tolerance of Synechococcus elongatus PCC 7942. Appl Environ Microbiol. 2018; 84(18). pii: e01222-18.

3. Tan X#, Yao L#, Gao Q, Wang W, Qi F and Lu X*. Photosynthesis driven conversion of carbon dioxide to fatty alcohols and hydrocarbons in cyanobacteria. Metab Eng. 2011;13:169-176.

4. Tan X, Zhu T, Shen S, Yin C, Gao H and Xu X*. Role of Rbp1 in the acquired chill-light tolerance of cyanobacteria. J Bacteriol. 2011;193:2675-2683.

5. Song K, Tan X*, Liang Y and Lu X*. The potential of Synechococcus elongatus UTEX 2973 for sugar feedstock production. Appl Microbiol Biotechnol. 2016;100:7865-7875.

6. Tan X#, Du W and Lu X*. Photosynthetic and extracellular production of glucosylglycerol by genetically engineered and gel-encapsulated cyanobacteria. Appl Microbiol Biotechnol. 2015;99:2147-2154.

7. Tan X#, Luo Q and Lu X*. Biosynthesis, biotechnological production, and applications of glucosylglycerols. Appl Microbiol Biotechnol. 2016;100:6131-6139.

8. Song K, Hagemann M, Tan X* and Lu X*. The response regulator slr1588 regulates spsA but is not crucial for salt acclimation of Synechocystis sp. PCC 6803. Front Microbiol. 2017;8:1176.

9. Tan X#, Liang F, Cai K and Lu X*. Application of the FLP/FRT recombination system in cyanobacteria for construction of markerless mutants. Appl Microbiol Biotechnol. 2013;97:6373-6382.

10. Tan X, Wang W and Lu X. Production of photosynthetic biofuels by genetically engineering cyanobacteria. Current Chemical Biology. 2012;6:26-31.

11. Gao Z#, Zhao H#, Li Z, Tan X and Lu X*. Photosynthetic production of ethanol from carbon dioxide in genetically engineered cyanobacteria. Energ Environ Sci. 2012;5:9857-9865.

12. Du W#, Liang F#, Duan Y, Tan X and Lu X*. Exploring the photosynthetic production capacity of sucrose by cyanobacteria. Metab Eng. 2013;19:17-25.

13. Savakis P, Tan X, Qiao C, Song K, Lu X, Hellingwerf KJ* and Branco Dos Santos F. Slr1670 from Synechocystis sp. PCC 6803 Is Required for the Re-assimilation of the Osmolyte Glucosylglycerol. Front Microbiol. 2016;7:1350.

14. Liu A, Tan X, Yao L and Lu X*. Fatty alcohol production in engineered E. coli expressing Marinobacter fatty acyl-CoA reductases. Appl Microbiol Biotechnol. 2013;97:7061-7071.

15. Savakis P, Tan X, Du W, Branco dos Santos F, Lu X and Hellingwerf KJ. Photosynthetic production of glycerol by a recombinant cyanobacterium. J Biotechnol. 2015;195:46-51.

16. Gao Q, Tan X and Lu X*. Enzymatic and physiological characterization of fatty acid activation in Synechocystis sp. PCC6803. J Basic Microbiol. 2013;53:848-855.

17. Qi F, Yao L, Tan X and Lu X. Construction, characterization and application of molecular tools for metabolic engineering of Synechocystis sp. Biotechnol Lett. 2013;35:1655-1661.

18. Yao L#, Qi F#, Tan X and Lu X*. Improved production of fatty alcohols in cyanobacteria by metabolic engineering. Biotechnol biofuels. 2014;7:94.

19. Luan G#, Qi Y#, Wang M, Li Z, Duan Y, Tan X and Lu X*. Combinatory strategy for characterizing and understanding the ethanol synthesis pathway in cyanobacteria cell factories. Biotechnol biofuels. 2015;8:184.

20. Wu W#, Zhang L#, Yao L, Tan X, Liu X and Lu X*. Genetically assembled fluorescent biosensor for in situ detection of bio-synthesized alkanes. Sci Rep. 2015;5:10907.

21. Zhu T#, Xie X#, Li Z, Tan X and Lu X*. Enhancing photosynthetic production of ethylene in genetically engineered Synechocystis sp. PCC 6803. Green Chem. 2015;17:421-434.

22. Zhu Z#, Luan G#, Tan X, Zhang H and Lu X*. Rescuing ethanol photosynthetic production of cyanobacteria in non-sterilized outdoor cultivations with a bicarbonate-based pH-rising strategy. Biotechnol biofuels. 2017;10:93.

23. Zhang L, Liang Y, Wu W, Tan X and Lu X*. Microbial synthesis of propane by engineering valine pathway and aldehyde-deformylating oxygenase. Biotechnol biofuels. 2016;9:80.

24. Duan Y#, Zhu Z#, Cai K, Tan X and Lu X*. De novo Biosynthesis of Biodiesel by Escherichia coli in Optimized Fed-Batch Cultivation. PLoS ONE. 2011;6:e20265.

四、专利

1. 吕雪峰,谈晓明,梁飞燕。一种用于构建无筛选标签蓝细菌的载体及其应用,ZL201310028228.7  (授权日期:2016413)

2. 吕雪峰,谈晓明,姚伦,高倩倩,齐凤霞。用于合成脂肪醇的构建体,载体,蓝细菌,以及在蓝细菌中生产脂肪醇的方法,ZL201010213758.5 (授权日期:2016413)

3. 吕雪峰,谈晓明,段仰凯,蔡轲,朱至。一种微生物体内合成生物柴油的方法,ZL200910241540.8 (授权日期:2013925)

4. 吕雪峰,齐凤霞,谈晓明,罗泉。一种集胞藻PCC6803表达外源基因的方法,ZL201010034404.4 (授权日期:2015122)

5. 吕雪峰, 杜伟, 谈晓明。一种用于合成甘油葡糖苷的工程菌和应用,ZL2013105981112 (授权日期:2018427)

五、获奖

1. 2017年“光驱固碳产能蓝细菌的人工设计与构建”获山东省科技奖(自然科学奖)二等奖(证书编号: ZR2017-2-8-R02,排名第二)

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