此页面上的内容需要较新版本的 Adobe Flash Player。

获取 Adobe Flash Player

 
    当前位置: 首页 > 资料下载 > 教授 > 正文
  • 王志斌
  • 作者:系统管理员    发布日期:2016-09-29    点击率:
  • 姓  名: 王志斌
    电子邮件: zbwang2000@yahoo.com
    通讯地址: 湖北省武汉市武昌区友谊大道368号湖北大学生命科学学院
    任职情况:湖北大学楚天学者特聘教授
    研究领域:环境表观遗传学

    一、学习和工作简历:
    2000-2006  Ph.D.    The Ohio State University,USA
    2006-2010  Postdoc.  NIH(National Heart,Lung,and Blood Institute)USA
    2010-      Assistant Professor (tenure-track)
     Bloomberg School of Public Health, Johns Hopkins University, USA
    2016-      湖北大学楚天学者特聘教授

    二、主持的代表性科研项目
    1. R01,NIH/NIEHS USA,04/01/16-03/31/21    
    Exposure-altered gene expression in five candidate imprinted loci for adult disease
    2. U01,NIEHS USA,07/01/16-06/30/21                                                                                  
    Epigenomics of Air Pollution driven Inflammation, Obesity and Insulin Resistance
    3. Kimmel Scholar Award,The Sidney Kimmel Foundation for Cancer Research,USA
       07/01/2012-06/30/2014
    Abnormal epigenetic codes mediated by DNMT1 and Mi-2/NuRD complex in cancer cells

    三、代表性论文(被引用总次数超过8300次)

    1. Li, Z., *Dai, H., Martos, SN, Xu, B., Gao, Y, Zhu, G., Li, T., Schones, D.E., and Wang, Z. (2015) Distinct roles of DNMT1-dependent and –independent methylation patterns in the genome of mouse embryonic stem cells. Genome Biology DOI: 10.1186/s13059-015-0685-2 (Impact factor 10.8)
    2. 2. Martos, S.N., Tang, W., and Wang, Z. (2015) Elusive inheritance: Transgenerational  effects  and epigenetic  inheritance in human environmental disease. Progress in Biophysics and Molecular Biology  (impact factor 3.5)
    3. Jin, Q., Zhuang, L., Lai, B., Wang, C., Li, W., Dolan, B., Wang, Z., Zhao, K., Peng, W., Dent, S., and Ge, K. (2014) Gcn5 and PCAF negatively regulate interferon  production through HAT-independent inhibition. EMBO Report (11):1192-201 (Impact factor 7.858)
    4. Dai, H., and Wang, Z. (2014) Histone modification patterns and their responses to environment. Current Environmental Health Reports 1:11-21 (Invited review)
    5. Wu, H., D'Alessio, A.C.D., Ito, S., Wang, Z., Cui, K., Zhao, K., Sun, Y.E., and Zhang, Y. (2011) Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes & Development 25:679-684 (231 citations) (impact factor 12.44)
    6. *Wu, H., *D'Alessio, A.C.D., Ito, S., Xia, K., Wang, Z., Cui, K., Zhao, K., Sun, Y.E., and Zhang, Y. (2011) Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473,389-393 (*Contribute equally) (294 citations) (impact factor 37.162)
    7. Daniel, J.A., *Santos, M.A., *Wang, Z., *Zang, C., Jankovic, M., Gazumyan, A., Kristopher R. Schwab, K.R., Yamane, A., Filsuf, D., Cho, Y-W., Ge, K., Nussenzweig, M.C., asellas, R., Dressler, G.R., Zhao, K., and Nussenzweig, A. (2010) PTIP promotes chromatin changes critical for immunoglobulin switch recombination. Science 329, 917-923 (*Co-second author) (70 citations) (impact factor 31.027)
    8. Qi, H.H., Sarkissian, M., *Hu, G-q., *Wang, Z., Bhattacharjee, A., Gordon, D.B., Lan, F., Ongusaha, P.P., Huarte, M., Yaghi, N.K., Lim, H., Garcia, B.A., Brizuela, L., Zhao, K., Roberts, T.M., and Shi, Y. (2010) Histone H3K9/H4K20 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature 466,503-507 (These authors contribute equally;  * These authors contribute equally to ChIP-seq) (119 citations) (impact factor 37.162)
    9. Zhou, J., Wang, C., Wang, Z., Dampier, W., Wu, K., Casimiro, M.C., Yu, Z., Wang, M., Liang, B., Chepelev, L., Popov, V.M., Sune, C., Quong, A., Lisanti, M.P., Tozeren, A., Zhao, K., and Pestell, R.G. (2010) Attenuation of forkhead signaling by the retinal determination factor DACH1. Proc Natl Acad Sci USA 107,6864-6869  (impact factor 9.737)
    10. Wang, Z., Zang, C., Cui, K., Schones, D.E., Barski, A., Peng, W., Zhao, K. (2009b) Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes. Cell 138,1019-1031 (impact factor 31.975) (611 citations)
    11. *Araki, Y., *Wang, Z., Zang, C., Wood, W. III., Schones, D. E., Lhotsky, B., Westo, R., Peng, W., Becker, K., Zhao, K., and Weng, N-p.  (2009) Genome-wide analysis of histone methylation reveals chromatin state-based complex regulation of gene transcription and function of memory CD8+ T cells. Immunity 30,912-925 (* co-first author) (impact factor 19.795)
    12. Wang, Z., Schones, D.E. and Zhao, K. (2009a) Characterization of human epigenomes. Current Opinion in Genetics and Development 19,127-134 (impact factor 8.23)
    13. Rosenfeld, J.A., Wang, Z., Schones, D.E., DeSalle, R., Zhao, K., Zhang, M. (2009) Determination of enriched histone modifications in non-genic portions of the human genome. BMC Genomics doi:10.1186/1471-2164/10/143 (121 citations) (impact factor 4.40)
    14. Wang, Z., Zang, C., Rosenfeld, J.A., Schones, D.E., Barski, A., Cuddapah, S., Cui, K., Roh, T-y, Peng, W., Zhang, M., Zhao, K. (2008).  Combinatorial patterns of histone acetylations and methylations in the human genome.  Nature Genetics 40, 897-903 (impact factor 35.209) (1168 citations)
    15. *Schones, D.E., *Cui, K., Cuddapah, S., Roh, T-y, Barski, A., Wang, Z., Wei, G., Zhao, K. (2008) Dynamic regulation of nucleosome positioning in the human genome. Cell 132,887-898 (*contribute equally) (impact factor 31.975) (811 citations)
    16. Barski, A., Cuddapah, S., Cui, K., Roh, T-y, Schones, D.E., Wang, Z., Wei, G., Chepelev, I., Zhao, K. (2007) Response: Mapping nucleosome positions using ChIP-Seq data. Cell 131, 832-833 (impact factor 31.975)
    17. *Barski, A., *Cuddapah, S., *Cui, K., *Roh, T-y, *Schones, D.E., *Wang, Z., *Wei, G., Chepelev, I., Zhao, K.(2007) High-resolution profiling of histone methylations in the human genome. Cell 129, 823-837 (*Contribute equally and are listed alphabetically) (Featured article) (impact factor 31.975) (The No. 3 most-cited biology paper of 2009 by The Scientist) (4067 citations) 

     

  • Copyright © 2006-2013 湖北大学生命科学学院 All Right Reservered  邮政编码:430062 电话:027-88661237 88663882 88661746 管理入口