教授

江正兵

发布时间:2013-09-06    点击率:

 

姓  名:江正兵

办公电话027-88663882

电子邮件zhbjiang@hubu.edu.cn 

研究领域:生物化工专业博士、教授、博士生导师,省部共建生物催化与酶工程国家重点实验室副主任,入选教育部新世纪优秀人才计划、湖北省新世纪高层次人才计划,获湖北省杰出青年科学基金、创新群体资助。主要关注分子酶工程、生物催化与转化、生物质资源综合利用等领域研究。

学习工作经历:

1993-1997年,湖北大学生命科学学院,生物学/理学学士

1997-2004年,湖北大学生命科学学院,实验师

1999-2002年,湖北大学生命科学学院,生物化学与分子生物学/理学硕士

2004-2007年,华东理工大学生物反应器工程国家重点实验室,生物化工/工学博士

2014-2015年,美国佐治亚州立大学,访问学者

2007-今, 湖北大学生命科学学院,副教授、教授


5年主持科研项目:

1. 新蛋白质元件人工设计合成及应用(2020YFA0908400),国家重点研发计划项目,2020.11~ 2025.10

2. 天然途径生化反应的机制解析与新砌块设计(2019YFA0905001),国家重点研发计划子课题,2020.01~ 2024.12

3. 高效农业微生物菌剂及新型肥料研制(2019ABA117),湖北省重大科技创新计划子课题,2019.01~ 2020.12

4. 生物质高效转化微生物菌剂技术开发(201910702001019),武汉合缘绿色生物股份有限公司横向课题,2019.10~ 2020.12

5. 生物酶协同效应在秸秆饲料化过程中的作用机制及应用研究(2018CFA019),湖北省自然科学基金创新群体,2018.1~2020.12

6. 秦巴山区农作物秸秆综合利用及生态农业集成示范(2018ZYYD-34),中央引导地方科技发展专项,2018.9~2020.8

7. 基于高效微生物菌剂的土壤改良技术研发及产品研制(2018ABA096),湖北省技术创新专项子课题,2018.1~2019.12

8. 基于协同效应的全细胞酶制剂开发及应用研究(2017020201010229),武汉市科技局应用基础研究项目,2017.1~2019.12

9. 秸秆资源饲料化高效利用关键技术研发(2017ABA139),湖北省技术创新专项子课题,2017.1~2018.12


发表主要论文(第一及通讯作者)

1.   Pan Hu, Huanan Li, Wenjing Xiao, Xiaohang Xie, Yuxian Yang, Lei Duan, Shanna Zhou, Yanmei Hu, Qiming Qiao, Qiuping Ran, Zhengbing Jiang*. Effect of Rhodococcus sp. pretreatment on cellulose hydrolysis of corn stalk, Preparative Biochemistry & Biotechnology, 2020, 5:1-7. DOI: 10.1080/10826068.2020.1799391.

2.  Wenjing Xiao, Huiting Song*, Huanan Li, Xu Li, Yuxian Yang, Pan Hu, Shanna Zhou, Yanmei Hu, Xinyi Xu, Zhuo Zhang, Zhengbing Jiang*. Effect of Different Biological Surfactants on Engineering Saccharomyces cerevisiae in Simultaneous Saccharification and Fermentation of Corncob. BioResources.2020, 15(2):2512-2524.

3.  Wenjing Xiao, Huanan Li, Wucheng Xia, Yuxian Yang, Pan Hu, Shanna Zhou, Yanmei Hu, Xiaopeng Liu, Yujun Dai, Zhengbing Jiang*. Co-expression of cellulase and xylanase genes in Sacchromyces cerevisiae toward enhanced bioethanol production from corn stover. Bioengineered. 2019, 10(1):513-521.

4.  Huanan Li, Chaoying Wang, Wenjing Xiao, Yuxian Yang, Pan Hu, Yujun Dai, Zhengbing Jiang*. Dissecting the effect of polyethylene glycol on the enzymatic hydrolysis of diverse lignocellulose. International Journal of Biological Macromolecules. 2019, 131: 676-681.

5.  Zi-Lu Liu, Hua-Nan Li, Hui-Ting Song, Wen-Jing Xiao, Wu-Cheng Xia, Xiao-Peng Liu,Zheng-Bing Jiang*. Construction of a trifunctional cellulase and expression in Saccharomyces cerevisiae using a fusion protein.. BMC Biotechnology. 2018,18:43.

6.  Hui-Ting Song, Yi-Min Yang, Ding-Kang Liu, Xiao-Qin Xu, Wen-Jing Xiao, Zi-Lu Liu, Wu-Cheng Xia, Cao-Yin Wang, Xiao Yu, Zheng-Bing Jiang*. Construction of recombinant Yarrowia lipolytica and its application in bio-transformation of lignocellulose. Bioengineered. 2017 Feb 17:1-6.

7.  Hui-Ting Song, Yuan Gao, Yi-Min Yang, Wen-Jing Xiao, Shi-Hui Liu, Wu-Cheng Xia, Zi-Lu Liu, Li Yi, Zheng-Bing Jiang*. Synergistic effect of cellulase and xylanase during hydrolysis of natural lignocellulosic substrates. Bioresource Technology 2016, 219:710-715.

8.  Hui-Ting Song, Wen-Jing Xiao, Yi-Min Yang, Yong Zhao, Yuan Gao, Shi-Hui Liu, Zi-Lu Liu, Wu-Cheng Xia, Rong Li, Nuo-Nan Li, Zheng-Bing Jiang*. Improving the anti-oxidation of glucose oxidase with computer-aided structure optimization, Journal of Advances in Biotechnology, 2016, 5 (3): 736-740.

9.  Hui-Ting Song, Shi-Hui Liu, Yuan Gao, Yi-Min Yang, Wen-Jing Xiao, Wu-Cheng Xia, Zi-Lu Liu, Rong Li, Xiang-Dong Ma, Zheng-Bing Jiang*. Simultaneous saccharification and fermentation of corncobs with genetically modified Saccharomyces cerevisiae and characterization of their microstructure during hydrolysis, Bioengineered, 2016, 7(3):198-204.

10.  Huiting Song, Jiashu Liu, Yang Liu, Huan Leng, Xu Li, Yong Zhao, Xiaosong Yang, Zhengbing Jiang*. Genetically modified Saccharomyces cerevisiae for one-step fermentation of bioalcohol using corncob as sole carbon source. Annals of Microbiology. 2014, 64: 781-785.

11.  Huiting Song, Rui Deng, Zhengbing Jiang*. High Efficient Fermentation of Natamycin with Streptomyces Gilvosporeus HBJ591. Bioproces. 2012, 2: 65-69.

12.  Huiting Song, Lichao Zhou, Lujia Zhang, Bei Gao, Dongzhi Wei, Yaling Shen, Rui Wang, Catherine Madzak, Zhengbing Jiang*. Construction of a whole-cell catalyst displaying a fungal lipase for effective treatment of oily wastewaters. Journal of Molecular Catalysis. B, Enzymatic. 2011 (71): 166-170

13.  XiaoSong Yang1, ZhengBing Jiang1, HuiTing Song, SiJing Jiang, Catherine Madzak and LiXin Ma. Cell-surface display of the active mannanase in Yarrowia lipolytica with a novel surface-display system. Biotechnology & Applied Biochemistry. 2009 (54):171–176.

14.  Zhengbing Jiang, Bei Gao, Ren Ren, Xingyi Tao, Yushu Ma and Dongzhi Wei. Efficient display of active lipase LipB52 with a Pichia pastoris cell surface display system and comparison with the LipB52 displayed on Saccharomyces cerevisiae cell surface. BMC Biotechnology. 2008, 8(1):4

15.  Zhengbing Jiang, Hui-Ting Song, Nishith Gupta, Li-Xin Ma and Zhen-Bin Wu. Cell surface display of functionally-active lipases from Yarrowia lipolytica in Pichia pastoris. Protein Expression and Purification. 2007, 56(1):35-39.

16.  Zhengbing Jiang, Hongping Wang, Yushu Ma and Dongzhi Wei. Characterization of two novel lipase genes isolated directly from environmental sample. Applied Microbiology and Biotechnology. 2006, 70(3): 327-332.

17.  HuiTing Song, Zheng-Bing Jiang*, LiXin Ma. Expression and purification of two lipases from Yarrowia lipolytica AS 2.1216. Protein Expression and Purification.2006, 47(2):393-397.

18.  Zhengbing Jiang, Yitao zheng, Yu Luo, Gang Wang, Hongping Wang, Yushu Ma, Dongzhi Wei. Cloning and expression of a novel lipase gene from Pseudomonas fluorescens B52. Molecular Biotechnology. 2005, 31(2):095-102.

19.  Zhengbing Jiang, Yitao zheng, Yu Luo, Gang Wang, Hongping Wang, Yushu Ma, Dongzhi Wei. Cloning and expression of a novel lipase gene from Pseudomonas fluorescens B52. Molecular Biotechnology. 2005, 31(2):095-102.


获奖情况:

12010年上海市科技进步奖一等奖:工业酶制剂的创制与产业化关键技术.

22011年武汉市科技进步奖三等奖:纳他霉素大规模发酵过程优化及提取纯化技术.

32016年全国商业科技进步奖一等奖:植物源生物活性物质精提用酶制剂的研发与应用.

42017年湖北省科技进步奖二等奖:生物酶理性改造与高效发酵关键技术及应用.


授权/申请专利:

1、纳他霉素高产菌株的选育及纳他霉素高效发酵提取纯化方法,专利号:ZL200810047019.6

2、一种纳他霉素提取纯化方法,专利号:ZL200910222792.6

3、一种提高葡萄糖氧化酶抗氧化性的方法,专利号:ZL201510428825.8

4、使用工程化的解酯耶氏酵母生产高蛋白秸秆饲料的方法,专利号:ZL201610227696.0

5、一种利用天然纤维素为唯一碳源进行同步糖化发酵的方法,申请号:201510418255.4

6、一种农作物秸秆酶解用复合酶及其工艺,申请号:201610152223.9

7、木聚糖降解与木糖利用的酿酒酵母及混合发酵方法,申请号:201711122870.6

8、一种多功能纤维素酶基因及其应用,申请号:201810807008.7

9、一种可降解木质纤维素的重组酿酒酵母菌株及其应用,申请号:201810806958.8

10、一种酚类污染物降解菌及其应用,申请号:201910233030.X

11、一种提高木质纤维素糖化效率的方法,申请号:201910910636.2

12、一种秸秆混合发酵饲料及其生产方法,申请号:201910911060.1

 

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